The cure for both types of tumors is surgery. If the tumor cannot be removed, chemotherapy is often given to try and prevent the tumor from growing further. The type of chemotherapy is different for each type of tumor.

In very rare situations, liver transplants are performed in patients who have neuroendocrine tumors which have spread to the liver. The rationale behind this is that because neuroendrocine tumors are so slow growing, removing the entire tumor in the liver with a transplant allows for several more years of life. Again, because pancreatic adenocaricnoma is faster moving, liver transplants are not offered in this disease when it has spread to the liver.