Can myelofibrosis cause weight loss and shoulder pain symptoms?

Health Description
Health Consultation Description: Hi Doctor. M7 65 yr old husband was diagnosed in 2012 with Myelofibrosis. He s been on thalidomide for 16 months. It had stem the progression of the condition. But he is experiencing strong inflamation in his feet and calves now . Pain in left shoulder sharp loss of weight. Are these symptoms of end stage ? He was diagnosed 5 years ago. Please advise.


Expert Reply

Condition analysis:
I understand your concerns. these are significant symptoms, however it is impossible to judge about the prognosis and if this is terminal stage or not. If he is in good general condition and heart and lung functions are fine then there is no need to be worried. his inflammations shoul dbe tredted with antibiotics and nonsteroid painkilllers or corticosterids if his condition allows that.

I hope I have answered you query. Kindly regards. Wish you a good health.

Instructions:
Symptoms of Myelofibrosis
Weakness and fatigue; heart palpitations; shortness of breath; paleness (pallor); loss of weight and appetite (due to anemia)
Easy bleeding and bruising; clusters of pinpoint-size hemorrhages (petechiae) on the skin (due to platelet insufficiency).
Fever and night sweats (due to overactive blood formation in the spleen and liver, or infection).
Bone pain (in some cases)
Attacks of gouty arthritis or kidney stones
Abdominal pain, fullness, or breathing difficulty (due to enlargement of the spleen and liver)
Frequent infections
Feeling run down or tired



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 Key words:  Myelofibrosis

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