Can thrombotic thrombocytopenic purpura cause heart diseases?

Health Description
Health Consultation Description: Can thrombotic thrombocytopenic purpura cause heart diseases?


Expert Reply

Condition analysis:
Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that causes blood clots (thrombi) to form in small blood vessels throughout the body. These clots can cause serious medical problems if they block vessels and restrict blood flow to organs such as the brain, kidneys, and heart. Resulting complications can include neurological problems (such as personality changes, headaches, confusion, and slurred speech), fever, abnormal kidney function, abdominal pain, and heart problems.[1] TTP can casue a variety of heart problems, including heart attack, arrhythmia, and congestive heart failure. Treatment of TTP with plasma exchange has greatly improved the chance of recovery from acute episodes of TTP.

Information regarding the long term health consequences of TTP is lacking, however the following recent articles explore this topic further and may be a helpful resource. These articles suggest that people with a history of TTP may be at an increased risk for long term neurological, kidney, blood vessel, and heart complications.

Instructions:
Diagnosis of thrombotic thrombocytopenic purpura
-- Complete medical history, physical examination and investigation procedures are used for diagnosis of ITP.
-- Secondary causes like leukemia, SLE, HIV, cirrhosis, hepatitis, congenital causes, drug induced (quinine, heparin) should be excluded.



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 Key words:  Thrombocytopenic purpura

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