Diabetes mellitus is a non -transmissible chronic disease of many causes. It can lead to some infections, cardiac and cerebrovascular pathological changes, renal failure, blindness, lower-limb gangrene, etc. and has become a main cause of mortality or disablement, bringing to the patient enormous psychological and spiritual oppression and bodily suffering.

In China the cultivation of mulberry trees has a history of more than seven thousand years. Mulberry trees of excellent quality are scattered almost all over China, which is the earliest country in the world growing mulberry trees, gathering mulberry leaves, feeding silkworms with them, and producing silk and silk fabrics. China is also the country where mulberry trees are cultivated in the greatest number in the world.

Taking into consideration the present situation that the number of patients of diabetes mellitus is increasing rapidly, that the Western medicines are limited in effectiveness, with toxic and side effects, and generally show loss of effectiveness after longtime use and that the means for preventing and treating complications of the disease are lacking, Chinese medical and pharmacological research and development institutes made a comprehensive study and analysis of the chemical ingredients of mulberry leaves and ascertained the material basis of the well-known suitability of these leaves for hypoglycemic use.

Mulberry-leaf is aimed chiefly at performing the function of inhibiting the postprandial rise of blood sugar. It can additionally prolong the acting time of human insulin and thereby lighten the burden on the pancreas, revive the pancreatic islet cells for the regular performance of their function, and stimulate them to secrete insulin. The alkaloid, polysaccharide and flavone in mulberry leaves are used in diabetes product as the three main ingredients for treating diabetes mellitus, and they act in unison and bring into full play their hypoglycemic capability with the result that the efficacy of lowering blood sugar is brought up to the full extent. After product made from mulberry-leaf for 5-7 days a great many diabetics have had their blood sugar (both fasting and postprandial) lowered by over 90%.