Source: Jingui Yaolue (Synopsis of Prescriptions of the Golden Cabinet).

Ingredients:
No. 1 Wuzhuyu (Fructus Evodiae) 9 g;
No. 2 Danggui (Radix Angelicae Sinensis) 6 g;
No. 3 Shaoyao (Radix Paeoniae) 6 g;
No. 4 Chuanxlong (Rhizoma Ligustici Chuanxiong)6g;
No. 5 Renshen (Radix Ginseng) 6 g
No. 6 Guizhi (Ramulus Cinnamomi) 6 g;
No. 7 Ejiao (Colla Corii Asini) (melted) 6 g;
No. 8 Mudanpi (Cortex Moutan Radicis) 5 g;
No. 9 Shengjiang (Rhizoma Zingiberis Recens) 6 g;
No. 10 Gancao (Radix Glycyrrhizae) 6 g;
No. 11 Banxia (Rhizoma Pinelliae) 6 g;
No. 12 Maimendong (Radix Ophiopogonis) 9 g.
 
Administration:
Decoct the above drugs in water for oral application.
 
Actions:
Warming the meridians and dispelling cold, removing blood stasis and nourishing blood.
 
Clinical Application:
This recipe is indicated for deficiency-cold in the thoroughfare vessel and conception vessel and accumulation of blood stasis, marked by irregular menstruation, preceded or delayed menstrual cycle, or Overdue or persistent menstrual duration, or repeated occurrence of menstruation within one month, or incessant metrostaxis, or dysmenorrhea, or amenorrhea, or failure to conceive due to cold in the uterine, and concomitant with fever at dusk, feverish sensation in palms, dry mouth and lips.

It is applicable to dysfunctional uterine bleeding, chronic pelvic inflammation, infertility and others that have chief manifestations as irregular menstruation, lower abdominal pain with cold sensation and constant dysphoria. Baishaoyao (Radix Paeoniae Alba) could be used for the purpose of nourishing yin and blood and Chishaoyao (Radix Paeoniae Rubra ) for clearing away heat and promoting blood circulation.

In case of sharp pain of the lower abdomen with cold sensation, subtract No.8 and No. 12 and add Aiye (Folium Artemisiae Argyi), or replace No. 6 with Rougui (Cortex Cinnamomi) to strengthen the effect of dispelling cold and relieving pain. If concomitant with qi stagnation, add Xiangfu (Rhizoma Cyperi) and Wuyao (Radix L inderae) to regulate the flow of qi and relieve pain. In case of persistent metrostaxis in light color, subtract No. 8 and add Aiye (Folium Artemisiae Argyi) and Shudihuang (Radix Rehmanniae Praeparatae) to warm meridians, nourish blood and arrest bleeding.

Elucidation:
This syndrome is caused by deficiency cold in the thoroughfare vessel and conception vessel and blood stasis, .which further affects blood generation and leads to heat. It should be treated by means of warming meridians to dispel cold, removing stasis and nourishing blood and with supplementary method of nourishing yin and clearing away heat. Ingredient No. 1 and No. 6 act as monarch drugs, which can warm meridians, dispel cold, and promote blood circulation. No. 2, No. 4 and No. 3 are used as minister drugs to promote blood flow, remove blood stasis, nourish blood and regulate menstruation. No. 8 bears the action of promoting blood flow and removing blood stasis, and clearing away heat from blood, while No. 7 and
No. 12 possess the function of nourishing blood and yin, moistening dryness and arresting bleeding. No. 5, No. 10, No. 11 and No. 9 can supplement qi and invigorate the spleen, warm the middle-energizer and regulate the stomach so as to promote transformation and digestion. The above seven ingredients play the part of adjuvant drugs. No. 10 also serves as guiding drug to mediate properties of other drugs. All ingredients together imply moistening action in warming action as well as tonic action in purgative action. Thus, this recipe is warm but not dry, and purgative but not drastic in nature.

Cautions:
This syndrome belongs to simultaneous occurrence of cold and heat, deficiency and excess syndromes, manifesting chiefly cold accumulation and blood stasis. Thus this recipe is contraindicated for cases with excess heat marked by feverish sensation in palms, sores and chest, reddened tongue and rapid pulse.