Liver qi stagnation is a term used in Traditional Chinese medicine. It has nothing to do with the physical organ liver.

The syndrome includes:
Primary: fullness and pain in the chest; depressed mood.

Secondary: tightness and discomfort in the chest area, frequent sighing, lack of appetite, difficulty in ejaculation during intercourse, Premature Ejaculation, Impotence, dislike talking, pain before and during menses (female), fullness in the breasts or breasts with lumps, pale tongue with thick fur, tight pulse.

A study using Beck Depression Inventory shows that most of the gan qi yu jie (liver qi stagnation) patients were depressed.

Another study shows that the increase of antidiuretic hormone is a significant correlative index of gan qi yu jie (liver qi stagnation). Gan qi stagnation is closely related with the function of regulating emotion of the central nervous system.